Can You Use One Wallet for NFTs, DeFi, and Bitcoin? Here's How

Managing NFTs, DeFi assets, and Bitcoin doesn't have to mean juggling multiple wallets. In this guide, we explore whether a single wallet can do it all—and how to choose one that combines NFT support, DeFi access, and Bitcoin compatibility. Discover what makes the best crypto wallet for NFT collectors and a powerful crypto DeFi wallet, all in one secure, easy-to-use app.

Jul 1, 2025 - 12:59
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Can You Use One Wallet for NFTs, DeFi, and Bitcoin? Here's How

As the crypto world expands, so do the use cases. From collecting digital art NFTs and earning yields through DeFi to holding Bitcoin as a long-term investment, managing multiple crypto assets can become overwhelming—especially when each category seems to require a different wallet. But what if you could simplify your experience and use one wallet for everything?

The good news is that modern wallets are becoming more versatile. In this article, we’ll explore whether a single wallet can support NFTs, DeFi platforms, and Bitcoin, what features to look for, and how to choose the best crypto wallet for NFT and a reliable crypto DeFi wallet—all in one.


1. The Challenge of Managing Diverse Crypto Assets

Historically, Bitcoin, Ethereum-based NFTs, and DeFi protocols have existed in separate ecosystems:

  • Bitcoin operates on its own blockchain with different wallet standards (e.g., BIP32, BIP39).

  • NFTs usually reside on Ethereum, Polygon, or Solana and require wallets that support ERC-721 or similar token standards.

  • DeFi platforms run on smart contract-compatible blockchains like Ethereum, BNB Chain, Avalanche, or Arbitrum, requiring interaction through Web3-enabled wallets.

This fragmentation has led users to manage multiple wallets—each with different interfaces, security settings, and backup phrases. Fortunately, cross-chain wallets are changing the game.


2. What to Look for in an All-in-One Crypto Wallet

If you want a single wallet that handles NFTs, DeFi, and Bitcoin, look for these essential features:

  • Multi-chain support: The wallet should support Ethereum, BNB Chain, Bitcoin, Polygon, Solana, and others.

  • Web3 compatibility: For interacting with dApps, the wallet must connect to smart contracts securely.

  • NFT visualization: The best crypto wallet for NFT should display your collectibles clearly, including metadata and images.

  • DeFi integration: A good crypto DeFi wallet allows you to access DeFi protocols, track your LP tokens, and monitor yields.

  • Bitcoin compatibility: Native support for Bitcoin (not just wrapped BTC) is crucial for long-term investors.


3. Wallets That Do It All: Are They Real?

Yes—wallets that unify NFT storage, DeFi access, and Bitcoin holdings do exist. While not all wallets offer full functionality across every network, some come close. Here are a few options:

Plus Wallet

A self-custodial, multi-chain wallet that supports NFTs, Bitcoin, and a variety of DeFi platforms. It’s ideal for users looking for a crypto DeFi wallet with built-in NFT viewing and cross-chain swaps. Plus Wallet is also optimized for performance on mobile devices, making it a strong candidate for the best crypto wallet for NFT enthusiasts on the go.

Trust Wallet

Popular for its extensive blockchain support, Trust Wallet allows you to store Bitcoin, interact with DeFi dApps, and manage NFTs across multiple chains. However, it can lack some advanced DeFi tracking tools and doesn't offer desktop support.

MetaMask (with Add-ons)

MetaMask is Ethereum-focused but supports DeFi and NFTs. With custom networks added (e.g., Polygon, BNB Chain), it becomes a flexible crypto DeFi wallet. However, MetaMask does not support native Bitcoin.

SafePal

Offers hardware and mobile options with broad support for Bitcoin, DeFi, and NFTs. It includes a dApp browser and permission management, though NFT features are still maturing.


4. Security Matters: Protecting Diverse Assets

The more assets your wallet holds, the more important security becomes. Here are tips to keep your all-in-one wallet safe:

  • Use a strong password and 2FA when possible.

  • Back up your seed phrase securely offline. Never share it.

  • Consider using a hardware wallet for long-term holdings and high-value assets.

  • Regularly check and revoke dApp permissions to avoid exposure.

Whether you’re managing NFTs or staking tokens, the wallet’s built-in security and transparency are essential.


5. How to Use One Wallet for Everything

Let’s say you choose a wallet like Plus Wallet. Here's how you can manage all three types of assets:

For NFTs

  • Connect to NFT marketplaces like OpenSea or Magic Eden.

  • View your NFTs directly in the wallet UI, including media files and metadata.

  • Send or receive NFTs across supported chains.

For DeFi

  • Use the in-app dApp browser to connect to platforms like Uniswap, Aave, or PancakeSwap.

  • Swap tokens, provide liquidity, or stake assets.

  • Track DeFi positions and manage token approvals securely.

For Bitcoin

  • Send and receive native BTC using SegWit or Legacy addresses.

  • Monitor Bitcoin price and balance.

  • Use QR code or address sharing for easy transfers.

All from one dashboard—no need to constantly switch between wallets.


6. Future Trends: Even More Interoperability

Wallet developers are racing toward better interoperability. With the rise of cross-chain bridges, wrapped assets, and unified interfaces, wallets are becoming the central hub for digital identity, finance, and ownership.

Expect future versions of top wallets to offer:

  • Cross-chain NFT transfers

  • DeFi position aggregation across chains

  • One-click staking and yield farming

  • Layer 2 scaling support for cheaper fees

As these innovations evolve, using a single wallet for everything won’t just be possible—it will be the norm.


Final Thoughts

So, can you use one wallet for NFTs, DeFi, and Bitcoin? Absolutely—if you choose the right one. A robust, multi-chain wallet that balances user experience with security can simplify your entire crypto journey.

Look for the best crypto wallet for NFT viewing and management, and ensure it doubles as a reliable crypto DeFi wallet with native Bitcoin support. By consolidating your assets in one secure app, you gain better control, easier navigation, and fewer risks—without sacrificing any functionality.